Protein Purification
MilliporeSigma™ Calbiochem™ Adenosine A2A Receptor Agonist I, CGS 21680, Hydrochloride
A xanthin derivative that acts as a potent agonist of adenosine A2A receptors (Ki =
MilliporeSigma™ Calbiochem™ Nocodazole
Inhibitor of mitosis.
MilliporeSigma™ Calbiochem™ Tpl2 Kinase Inhibitor
The Tpl2 Kinase Inhibitor, also referenced under CAS 871307-18-5, controls the biological activity of Tpl2 Kinase.
MilliporeSigma™ Calbiochem™ PERK Inhibitor I, GSK2606414
GSK2606414 is a cell-permeable, highly potent inhibitor of EIF2AK3/PERK (IC50 = 0.4 nM; [ATP] = 5 μM). Targets PERK in its inactive DFG conformation at the ATP-binding region.
MilliporeSigma™ Calbiochem™ SIRT1 Inhibitor IV, (S)-35
The SIRT1 Inhibitor IV, (S)-35, also referenced under CAS 848193-72-6, controls the biological activity of SIRT1. This small molecule/inhibitor is primarily used for Cell Structure applications.
MilliporeSigma™ Calbiochem™ AICA-Riboside
AICA-Riboside, CAS 2627-69-2, is a cell-permeable nucleoside compound whose phosphorylated metabolite activates AMPK and acts as a regulator of de novo purine synthesis.
MilliporeSigma™ Calbiochem™ InSolution™ Interleukin-1 Receptor-Associated-Kinase-1/4 Inhibitor
The Interleukin-1 Receptor-Associated-Kinase-1/4 Inhibitor controls the activity of Interleukin-1 Receptor-Associated-Kinase-1/4. Primarily used for Phosphorylation & Dephosphorylation apps.
MilliporeSigma™ Calbiochem™ Cathepsin L Inhibitor IV
The Cathepsin L Inhibitor IV controls the biological activity of Cathepsin L. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
MilliporeSigma™ Calbiochem™ TAPI-2
TAPI-2, CAS 187034-31-7, is a hydroxamate-based inhibitor of MMPs and TACE. Inhibits the activation-induced shedding of L-selectin from neutrophils, eosinophils, and lymphocytes.
MilliporeSigma™ Calbiochem™ Syk Inhibitor III
The Syk Inhibitor III, also referenced under CAS 1485-00-3, controls the biological activity of Syk. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ Ro-32-0432
A selective cell-permeable protein kinase C inhibitor.
MilliporeSigma™ Calbiochem™ TrpA1 Antagonist, HC-030031
The TrpA1 Antagonist, HC-030031, also referenced under CAS 349085-38-7, controls the biological activity of TrpA1. This small molecule/inhibitor is primarily used for Neuroscience applications.
MilliporeSigma™ Calbiochem™ Gβγ Modulator II, Gallein
A cell-permeable xanthene compound that binds to Gβγ with high affinity (K
MilliporeSigma™ Calbiochem™ Guanosine 3',5'-cyclic Monophosphate, 8-Bromo-, Sodium Salt
Cell-permeable cGMP analog that is more resistant to phosphodiesterases than cGMP.
MilliporeSigma™ Calbiochem™ TRPV4 Agonist, GSK1016790A
A cell-permeable, potent, selective agonist of TRPV4 channel. Enhances Ca2+ flux in a variety of human and mouse cells (EC50 = 2.1 nM for human TRPV4).